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【结 构 式】 
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【药物名称】 【化学名称】N-(2-Isopropoxybenzyl)-1,6-naphthyridine-2-carboxamide 【CA登记号】 【 分 子 式 】C19H19N3O2 【 分 子 量 】321.38218 |
【开发单位】Shire BioChem (Originator) 【药理作用】ANTIINFECTIVE THERAPY, Antiviral Drugs |
合成路线1
The condensation of 1,6-naphthyridine-2-carboxylic acid (I) with 2-isopropoxybenzylamine (II) by means of EDC and HOBT in DMF yields the target compound.
| 【1】 May, S.; Stefanac, T.; Jin, H.; Wang, W.; Yuen, L.; Falardeau, G.; Lavallee, J.-F.; Bedard, J.; Chan, L.; Discovery of 1,6-naphthyridines as a novel class of potent and selective human cytomegalovirus inhibitors. J Med Chem 1999, 42, 16, 3023. |
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