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【结 构 式】 
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【药物名称】RS-2232 【化学名称】4-[(6,7-Dihydro-5H-cyclopentapyrimidin-4-yl)amino]benzonitrile 【CA登记号】85073-83-2 【 分 子 式 】C14H12N4 【 分 子 量 】236.27854 |
【开发单位】Sankyo (Originator) 【药理作用】Antidepressants, Mood Disorders, Treatment of, PSYCHOPHARMACOLOGIC DRUGS |
合成路线1
By condensation of 4-chloro-6,7-dihydro-5H-cyclopenta[dlpyrimidine (I) with 4-cyanoaniline (II) in ethanol at 130 C.
| 【1】 Kamioka, T.; et al. (Sankyo Co., Ltd.; Ube Industries, Ltd.); Pyrimidine derivatives and a pharmaceutical composition containing them. CA 1169861; EP 0067630; JP 57203072; US 4450162 . |
| 【2】 Serradell, M.N.; Castaner, J.; RS-2232. Drugs Fut 1985, 10, 6, 469. |
Extended Information