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【结 构 式】 
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【药物名称】BRL 26314 【化学名称】N-(4-Chlorobenzyl)-L-phenylalanine 【CA登记号】79600-96-7 【 分 子 式 】C16H16ClNO2 【 分 子 量 】289.76442 |
【开发单位】GlaxoSmithKline (Originator) 【药理作用】Lipoprotein Disorders, Treatment of , METABOLIC DRUGS |
合成路线1
By reductocondensation of 4-chlorobenzaldehyde (I) with L-phenylalanine (II) by means of cyanoborohydride in methanol.
| 【1】 Ferres, H. (SmithKline Beecham plc); N-Substituted alpha-aminoacids, processes for making them and pharmaceutical compositions containing them. EP 0031653; ES 497907; JP 56092843 . |
| 【2】 Castaner, J.; Serradell, M.N.; Thorpe, P.; BRL-26314. Drugs Fut 1985, 10, 1, 12. |
Extended Information