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【结 构 式】 
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【药物名称】IVX-Q-101, WAX-120337, AS-101, Ossirene 【化学名称】Ammonium trichloro(dioxyethylene-O,O')tellurate 【CA登记号】106566-58-9 【 分 子 式 】C2H8Cl3NO2Te 【 分 子 量 】312.05056 |
【开发单位】Bar-Ilan University (Originator), Baker Norton (Licensee) 【药理作用】IMMUNOMODULATING AGENTS, Immunomodulators |
合成路线1
A new synthesis of AS-101 has been reported: By reaction of tellurium tetrachloride (I) with ethylene glycol (II) and ammonium chloride (III) at 80 C. A mechanism for the unusual synthesis in refluxing acetonitrile, reported previously in the original monograph, is also suggested.
| 【1】 Tamari, T.; Sredni, B.; Albeck, M.; Synthesis and properties of ammonium trichloro(dioxyethylene-O,O')tellurate (AS-101). A new immunomodulating compound. Synthesis 1989, 8, 8, 635. |
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