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【结 构 式】 
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【药物名称】CVT-P040 【化学名称】1-(2-Phenylethyl)-1-(2-propynyl)hydrazine 【CA登记号】 【 分 子 式 】C11H14N2 【 分 子 量 】174.24763 |
【开发单位】CV Technologies (Originator) 【药理作用】Antidepressants, Mood Disorders, Treatment of, PSYCHOPHARMACOLOGIC DRUGS, MAO-A Inhibitors, MAO-B Inhibitors |
合成路线1
The condensation of 2-phenylethylhydrazine (I) with propargyl bromide (II) by means of K2CO3 in aqueous acetonitrile gives the target hydrazine.
| 【1】 Sloley, B.D.; Urichuk, L.J.; Pang, P.K.T.; Coutts, R.T.; Shan, J.J.; Baker, G.B.; Ling, L.; Synthesis of N-propargylphenelzine and analogues as neuroprotective agents. Bioorg Med Chem Lett 2001, 11, 20, 2715. |
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