• English
  • 简体中文
Login Register
Current Location: Home > Feedback Help Print

【结 构 式】

【药物名称】AMD-6221

【化学名称】Potassium dihydrogen (OC-6-45)-[N-[2-[bis[(carboxy-kappaO)methyl]amino-kappaN]ethyl]-N-[2-[bis(carboxymethyl)amino]ethyl]glycinato(5-)-kappaN,kappaO]chlororuthenate(3-) monohydrate

【CA登记号】294644-98-7

【 分 子 式 】C14H22ClKN3O11Ru

【 分 子 量 】583.96994

【开发单位】AnorMED (Originator)

【药理作用】IMMUNOMODULATING AGENTS, Treatment of Transplant Rejection, Nitric Oxide Scavengers

合成路线1

The title compound is obtained by complexation of diethylenetriaminopentaacetic acid (I) with potassium pentachloroaquoruthenium(III) in boiling diluted HCl.

1 Mosi, R.; et al.; Mechanistic studies on AMD6221: A ruthenium-based nitric oxide scavenger. Biochem Biophys Res Commun 2002, 292, 2, 519.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 55225 2-(bis{2-[bis(carboxymethyl)amino]ethyl}amino)acetic acid C14H23N3O10 详情 详情
Extended Information