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【结 构 式】

【药物名称】Felbamate, W-554, Felbamyl, Taloxa, Felbatol

【化学名称】2-Phenyl-1,3-propanediol dicarbamate

【CA登记号】25451-15-4

【 分 子 式 】C11H14N2O4

【 分 子 量 】238.24523

【开发单位】MedPointe (Originator), National Institutes of Health (Not Determined), Schering-Plough (Licensee)

【药理作用】Antiepileptic Drugs, Bipolar Disorder, Treatment of, Mood Disorders, Treatment of, NEUROLOGIC DRUGS, PSYCHOPHARMACOLOGIC DRUGS

合成路线1

By an ester-exchange reaction between 2-phenylpropane 1 3-diol (I) in ethyl carbamate (II).

1 Ludwig, B.J.; et al.; Carbamate derivatives related to meprobamate. J Med Chem 1969, 12, 3, 462.
2 Prous, J.; Castaner, J.; Felbamate. Drugs Fut 1986, 11, 11, 931.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 24198 2-phenyl-1,3-propanediol C9H12O2 详情 详情
(II) 24199 Ethyl carbamate; Urethane 51-79-6 C3H7NO2 详情 详情
Extended Information