【结 构 式】 |
【药物名称】Felbamate, W-554, Felbamyl, Taloxa, Felbatol 【化学名称】2-Phenyl-1,3-propanediol dicarbamate 【CA登记号】25451-15-4 【 分 子 式 】C11H14N2O4 【 分 子 量 】238.24523 |
【开发单位】MedPointe (Originator), National Institutes of Health (Not Determined), Schering-Plough (Licensee) 【药理作用】Antiepileptic Drugs, Bipolar Disorder, Treatment of, Mood Disorders, Treatment of, NEUROLOGIC DRUGS, PSYCHOPHARMACOLOGIC DRUGS |
合成路线1
By an ester-exchange reaction between 2-phenylpropane 1 3-diol (I) in ethyl carbamate (II).
【1】 Ludwig, B.J.; et al.; Carbamate derivatives related to meprobamate. J Med Chem 1969, 12, 3, 462. |
【2】 Prous, J.; Castaner, J.; Felbamate. Drugs Fut 1986, 11, 11, 931. |
Extended Information