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【结 构 式】 
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【药物名称】Pirozadil, 722D, Pemix 【化学名称】3,4,5-Trimethoxybenzoic acid 2,6-pyridinediylbis(methylene)ester 【CA登记号】54110-25-7 【 分 子 式 】C27H29NO10 【 分 子 量 】527.53288 |
【开发单位】Almirall Prodesfarma (Originator) 【药理作用】Lipoprotein Disorders, Treatment of , METABOLIC DRUGS |
合成路线1
Prepared from 3,4,5-trimethoxybenzoic acid (I) by treatment with thionyl chloride in benzene to give the acyl chloride (II), which is treated with 2,6-pyridinedimethanol (III) in pyridine.
| 【1】 (Almirall Prodesfarma, SA); Method of preparing bis(3,4,5-trimethoxybenzoate) of pyridine-2,6-dimethanol. ES 1401608 . |
| 【2】 Williams, R.; Pirozadil. Drugs Fut 1981, 6, 5, 290. |
Extended Information