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【结 构 式】 
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【药物名称】Milacemide, CP-1552-S, Glyzan, Glyzac 【化学名称】2-(Pentylamino)acetamide 【CA登记号】76990-56-2, 76990-85-7 (monoHCl), 79922-20-6 (phosphate(1:1)), 79912-65-5 (sulfate(1:1)) 【 分 子 式 】C7H16N2O 【 分 子 量 】144.21837 |
【开发单位】Pfizer (Originator) 【药理作用】Antidepressants, Antiepileptic Drugs, Antiparkinsonian Drugs, Cognition Disorders, Treatment of, Extrapyramidal Disorders, Treatment of, Mood Disorders, Treatment of, NEUROLOGIC DRUGS, PSYCHOPHARMACOLOGIC DRUGS |
合成路线1
By condensation of pentylamine (I) with chloroacetamide (II) by means of NaHCO3 in methanol.
| 【1】 Roncucci, R.; Gillet, C.; Cordi, A.; Martens, M.; Roba, J.; Niebes, P.; Lambellin, G.; Van Dorsser, W.; Derivatives of glycinamide, their preparation and their use. DE 3010599; FR 2451913; GB 2048852; US 4639468 . |
| 【2】 Serradell, M.N.; Castaner, J.; Milacemide. Drugs Fut 1984, 9, 8, 587. |
Extended Information